Digital health that works with communities. in real time. in context. across borders.
Welcome
Dr. Roman Shrestha
Director, Shrestha Lab
Our mission is to develop, optimize, and implement digital health interventions that advance health equity and improve outcomes in underserved communities — across the U.S. and around the world.
Our work spans HIV prevention and treatment, substance use and harm reduction, mental health, smoking cessation, and sexual and gender minority health.
We design and evaluate technology-enabled interventions that fit the realities of everyday life. Our research combines mobile and wearable technologies, real-time assessment, adaptive interventions, AI, and rigorous experimental and implementation methods.
The right intervention. At the right moment. In the right context.
We ask not only whether an intervention works, but what works, for whom, when, and under what conditions.
We partner with academic institutions, community organizations, healthcare systems, and industry in the United States and globally to translate rigorous science into accessible, scalable interventions that respond to community needs and priorities.
Research Focus
Community-engaged.
Evidence-driven.
Digital health interventions
Integrating emerging technologies into personalized, scalable, and effective health interventions.
Adaptive designs
Developing and testing interventions that adapt to people’s needs and changing circumstances.
HIV prevention & care
Improving outcomes across the HIV prevention, treatment, and care continuum.
Substance use
Improving health outcomes through substance use prevention, cessation, and harm reduction.
Digital health · Adaptive design
A real-time JITAI check-in from the JomCare app — support that adapts to how someone's doing right now.
Mental health
Improving mental health outcomes through timely, personalized, and community-centered interventions.
Global health
Building evidence for healthier communities across countries and cultures.
People
A global team built on mentorship and collaboration.
Publications
Latest publications.
Get Involved
What brings you here?
Most common path
Graduate training
Pursue rigorous graduate training through research, mentorship, and collaboration. Develop expertise in health research and digital health.
See how to apply →
Undergraduate research
Gain hands-on research experience through mentorship and ongoing studies. Build skills in research methods, data, and scientific communication.
Get started →
Take part in research
Help advance research addressing important health needs in diverse communities. Participate in studies focused on HIV, mental health, substance use, and related topics.
Find a study →
Collaborate with us
Collaborate with us on research addressing important and emerging health challenges. We welcome partnerships across disciplines, institutions, and communities.
Start a conversation →